CV091198

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHT---NLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRN----PTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDR 723
            V++ G+ W+ GDG  +  W D WV   PL  L  G      +  +     I    W    ++     N    +  + +       D  +W  S +G FS  +AY+++  +    P   + +  +WK++ P + KTF+WL+ +  + T   R RR +   + C  C    E + H+ R C   + +W ++  +   +  F   + +W+   L     + +    + W+T+F   +W  WK R
Sbjct:  168 VVSHGVGWIPGDGQQIRFWTDRWVSGKPLLELDNGERPTDCDTVVAKDLWIPGRGWDFAKIDPYTTNNTRLELRAVVLDLVTGARDRLSWKFSQDGQFSVRSAYEMLTVDEVPRPNMASFFNCLWKVRVPERVKTFLWLVGNQAVMTEEERHRRHLSASNVCQVCKGGVESMLHVLRDCPAQLGIWVRVVPQRRQQGFFSKSLFEWLYDNL----GDRSGCEDIPWSTIFAVIIWWGWKWR 404          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPG-NHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTG-WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFEN 744
            I++A   +  G    +G G+ V +W D W+    L S+ P  N ++ ++ V  L  +G W L++L                                            L +R+  DNTG W W+ KLK   K K  IWLIFH  LPTN +R RR +     CP C  + ED  H  R C ++ E+W +L       N     I DW+  Q+   + +           LFL+ LW IW+ RN  +FEN
Sbjct:  191 IIRALQHLREGFMIRLGTGD-VSIWYDKWLEFGRLASILPAVNISDTNMLVKDLWDDGQWNLESL--------------------------------------------LRSRHMEDNTGKWHWLVKLKAIKKVKHLIWLIFHGCLPTNTLRFRRRLTDNQGCPCCQFAVEDTWHCIRDCRRAWEVWQELGFIG-ATNFLGGNIVDWIIQQVDSDQGH-----------LFLSALWWIWRQRNCFAFEN 382          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPG-NHTNLSIKVS---YLIVN-----GSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLIN-RNPTDNTG-WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWN---KLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAKLSIIMQ 792
            I K    + +   W +G+G  +  W+D W     L+S  P  NH    ++V    Y + +     G+W      H I   I+  I+    P    + D   W +S NG  +   AY ++  R   D    W+ I K +   + K F+W + HN + TN +R RR +     C  C    E L H  R C K+ ++W    K++ R L  +      Q+W    +  +   +       W+  F   LW IWK+R  + F  +D    N  ++SI+++
Sbjct: 1058 ICKEWDTVNQNATWNVGNGKQILFWRDSW-----LESYGPIINHLEREVQVDTLDYTVADMVDDRGNWKWDVFAHLIPMQIVMSIVGYTPPMQDGIDDTVGWDHSSNGKLTVRTAYMVLEERGEMDQDPIWRLIRKWQGMERIKVFLWTVAHNSIMTNDLRYRRHLTANRFCDHCGTEVETLTHALRDCPKARKIWEVFVKVENRELFFS------QNWYAWLVSNMSARNRNTDHGAWSLEFGIALWYIWKERCNRVF-GVDQG-KNKEQVSILIK 1321          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVNGSW----------YLQNLNHPIDE--NIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTG--WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDS--CPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDAN 756
            V T   K+++G+G+    W D W+GDSPL   +P  +   S K + +   G W          + + L H   E  +I++ +L+ + P F    D   W  + +G+FS  +   ++++           ++W   +P K + F+WL+  +K+ T     +   +TL    C  CN S E  +HLF  C  +  +W KL     + + F   + D        ++        L W  LF   +W +W  RN   F +   N
Sbjct: 1492 VFTNHCKFMVGNGSLTSFWLDNWIGDSPLKIAFPRLYLLSSSKSALVADMGRWSNGIWLWSLQWRRPLFHFEQEQLSILSSLLE-SKPMFCHKMDKKIWTLTSDGLFSVKSCSKIMDQLLYGGAKPFQSFVWIKLSPPKVQLFLWLLVQDKVTTRDFLFQHDYLTLQESRCAFCNKSLESTSHLFIHCYFTWNIWMKLLANRGVCSVFPKSVDDMCYQWSSMVKGE---QQNLSWEFLFSCVVWNLWLHRNDVIFNDTAPN 1748          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVNGSW----------YLQNLNHPIDE--NIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTG--WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDS--CPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDAN 756
            V T   K+++G+G+    W D W+GDSPL   +P  +   S K + +   G W          + + L H   E  +I++ +L+ + P F    D   W  + +G+FS  +   ++++           ++W   +P K + F+WL+  +K+ T     +   +TL    C  CN S E  +HLF  C  +  +W KL     + + F   + D        ++        L W  LF   +W +W  RN   F     N
Sbjct:   92 VFTNHCKFMVGNGSLTSFWLDNWIGDSPLKIAFPRLYLLSSSKSALVADMGRWSNGIWLWSLQWRRPLFHFEQEQLSILSSLLE-SKPMFCHKMDKKIWTLTSDGLFSVKSCSKIMDQLLYGGAKPFQSFVWINLSPPKVQLFLWLLVQDKVTTRDFLFQHDYLTLQESRCAFCNKSLESTSHLFIHCHFTWNIWMKLLANQDVCSVFPKSVDDMCYQWSSMVKGE---QQNLSWELLFSCVVWNLWLHRNDVIFNETAPN 348          

Query:    1 GILKANPVITRGMKWVIGDGNSVDLWKDWWV-GDSPL----DSLYPGNHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAY----DLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRG-CLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHW 678
            GI K  P IT+G+ WV+G  + V  WKD W+ G  PL      + P    N S+    +   G W  +   H +   ++ ++   N P      D   W +S  G FS ++AY    D    +  ++  WK IW+ K   + K F+W + H  + TN +R RR I +   C  C    E + H  R  C  +  +W+++ +    R  F S   +W T  L  +R+N+     + W
Sbjct:  305 GICKVWPSITQGVNWVLGCRSKVLFWKDSWLEGYGPLHMHTSQIIPEVMLNCSV-ADMVDDRGQWQWETFAHFLPIQVILILAGYNPPTPQLGEDKVYWRHSTGGQFSVNSAYRIQEDSRATHQQNDPLWKIIWQWKGLERVKIFLWTVAHGAIMTNEVRWRRKITSNPCCSNCLTELETIIHALREYCPNARGVWDRI-IEVADREAFYS--LNWYTWLLNNLRDNTKQRVCIGW 536          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVS---YLIVN-----GSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLIN-RNPTDNTG-WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWN---KLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSF 738
            I K    + +   W +G+G  +  W+D W+  + L      NH    ++V    Y + +     G+W      H I   I+  I+    P    + D   W +S N   +   AY ++  R   D+   W+ I K +   + K F+W + HN + TN +R RR +     C  C    E L H  R C K+ ++W    K++ R L  +      Q+W    +  +   +       W+  F   LW IWK+R  + F
Sbjct:   68 ICKEWDTVNQNATWNVGNGKRILFWRDSWLESNGLII----NHLEREVQVKTLDYTVADMVDDRGNWKWDVFAHLIPMQIVMSIVGYTPPMQDGIDDMVGWDHSSNEKLTVRTAYMVLEERGEMDHDLIWRLIRKWQGMKRIKVFLWTVAHNSIMTNDLRYRRHLTANRFCDHCGTEVETLTHALRDCPKARKIWEVFVKVENRELFFS------QNWYAWLVSNMSARNRNTDHGAWSLEFGIALWYIWKERCNRVF 315          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVNGSW----YLQNL--NHPI---DENIMNLILDI--NIPQFAQVADHPTWVNSDNGMFSSSAAYDLINR------NPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDS--CPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQD----WVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDAN 756
            V T   K+++G+G+    W D W+GD PL + +P  +   S K + +   G W    +L +L    P+   ++  ++L+  +  + P F    D   W  + +G+FS  +   ++++       P  ++    +W   TP K + F+WL+  +K+ T     +   +TL    C   N S E  +HLF  C  +  +W KL       + F   + D    W ++   K +N       L W  LF   +W +W  RN   F +   N
Sbjct:  127 VFTNHCKFMVGNGSLTSFWLDNWIGDYPLKTAFPRLYLLSSSKSALVADMGRWSNGIWLWSLQWRRPLFHFEQEQLSLLSSLLESKPMFCHKMDKKIWTLNSDGLFSVKSCSKMMDQLLYGGAKPFQSS----VWIKLTPPKVQLFLWLLVQDKVTTRDFLFQHDYLTLQESRCAFYNKSLESSSHLFIHCHFTWNIWMKLLSNRGFCSVFPKSVDDMCYQWSSMVKGKWQN-------LSWQLLFSCVVWNLWLHRNDVIFNDAPPN 383          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVNGSW----YLQNL--NHPI---DENIMNLILDI--NIPQFAQVADHPTWVNSDNGMFSSSAAYDLINR------NPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDS--CPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQD----WVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDAN 756
            V T   K+++G+G+    W D W+GD PL + +P  +   S K + +   G W    +L +L    P+   ++  ++L+  +  + P F    D   W  + +G+FS  +   ++++       P  ++    +W   TP K + F+WL+  +K+ T     +   +TL    C   N S E  +HLF  C  +  +W KL       + F   + D    W ++   K +N       L W  LF   +W +W  RN   F +   N
Sbjct:  127 VFTNHCKFMVGNGSLTSFWLDNWIGDYPLKTAFPRLYLLSSSKSALVADMGRWSNGIWLWSLQWRRPLFHFEQEQLSLLSSLLESKPMFCHKMDKKIWTLNSDGLFSVKSCSKMMDQLLYGGAKPFQSS----VWIKLTPPKVQLFLWLLVQDKVTTRDFLFQHDYLTLQESRCAFYNKSLESSSHLFIHCHFTWNIWMKLLSNRGFCSVFPKSVDDMCYQWSSMVKGKRQN-------LSWQLLFSCVVWNLWLHRNDVIFNDAPPN 383          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVNGSW----------YLQNLNHPIDE--NIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTG--WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDS--CPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDAN 756
            V T   K+++G+ +    W D W+GDSPL   +P  +   S K + +   G W          + + L H   E  +I++ +L+ + P F    D   W  + +G+F+  +   ++++           ++W   +P K + F+WL+  +K+       +   +TL    C  CN S E  +HLF  C  +  +W KL     + + F   + D        ++        L W  LF   +W +W  RN   F +   N
Sbjct: 1003 VFTNHCKFMVGNDSLTSFWLDNWIGDSPLKIAFPRLYLLSSSKSALVADMGRWSNGIWLWSLQWRRPLFHFEQEQLSILSSLLE-SKPMFCHKMDKKIWTLTSDGLFNVKSCSKIMDQLLYGGAKPFQSFVWIKLSPPKVQLFLWLLVQDKVTIRDFLFQHDYLTLQESRCAFCNKSLESTSHLFIHCHFTWNIWMKLLANRGVCSVFPKSVDDMCYQWSSMVKGE---QQNLSWELLFSCVVWNLWLHRNDVIFNDTAPN 1259          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVNGSW----------YLQNLNHPIDE--NIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTG--WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDS--CPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQD----WVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAKLSIIMQ 792
            V T   K+++G+G+    W D W+GD PL + +P  +   S K + +   G W          + + L H   E  ++++ +L+  +  F    D   W  + +G+FS  +   ++++   D        +W   TP K + F+ L+  +K+ T     +   +TL    C  CN S E  +HLF  C  +  +W KL       + F   + D    W ++   K +N       L W  LF   +W +W  RN   F   DA P+     S++ Q
Sbjct:  648 VFTNHCKFMVGNGSLTSFWLDNWIGDYPLKTAFPRLYLLSSSKSALVADMGRWSNGIWLWSLQWRRPLFHFEQEQLSLLSSLLESKL-MFCHKMDKKIWTLNSDGLFSVKSCSKMMDQLLYDGAKPFQSSVWIKLTPPKVQLFLSLLVQDKVTTRDFLFQHDYLTLQESRCAFCNKSLESSSHLFIHCHFTWNIWMKLLSNRGFCSLFSKSVDDMCYQWSSMVKGKQQN-------LSWQLLFSYVVWNLWLHRNDVIFN--DAAPNLQICFSMVRQ 914          

Query:   25 ITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVS---YLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFE---NIDANPSNSAKLSIIMQWKLT 804
            + +G+ W +G+G     W D W+G   L      +  N+ ++V    +L VNG W L  L+  + + I+N ++ I+  +   + D   W     G  +    +               +WK+  P K   F+W + H KL TN  R   G+    SCPRC+   EDLNHLFR C +S ELW KL++    +    +   DW+ + LK  + +   N+  H   L   +L  IWK R K  FE   ++D  P     L  + +WK T
Sbjct:   18 LEQGLVWHVGNGQKTRFWLDNWLGIGHLLLHAQCSTPNVLLQVKVYHFLDVNG-WRLDQLSGLLPQAILNNVIGIHAVKDGDIEDKIRW-----GFIADDRVF---------------LWKINAPPKVLHFLWKVCHRKLLTNSHRIHIGLSFDASCPRCSCICEDLNHLFRNCSESAELWRKLNMGTNGQLVNLNDFWDWLMLNLKFSKTDFRGNTYSH---LVAFSLLNIWKMRCKGGFEPDPHLD-TPLEIGVLRDLTEWKDT 258          

Query:  151 VSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSA 771
            +S  + +G W L  L   + E I+ +IL ++    +   D   W ++ NG F+                   +IW L  P K KTF+W + H KL TN  R RRG+  + +C RCN   E + HLF  C  S+ +W+ L               +W+   LK +++   +   L W+ +F   +W IWK R      N D + S S+
Sbjct:  135 LSDFLEDGVWDLPCLRECLPETIVQMILCVHAGLPSSGNDKCIWRHTGNGSFT-------------------FIWNLPVPPKIKTFLWTVCHGKLLTNVQRQRRGLTQVPACSRCNYPMETIAHLFMYCPYSLSIWDNLPT-------------EWL---LKNLQSKKKVYHGLPWHLVFTNFMWFIWKWRTGTCKINTDGSRSPSS 306          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDS--LYPGNHTNLSIKVSYLIVN--GSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLIN------RNPTDNTG-------WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAKLSII 786
            +L+   ++ RG  W + +G  + LW D W+ +S  D   L+     + +++V  +I      W L  + H I ++    I  +     +++ D   W    NG +S  + Y  ++      RNP  ++        WK IWK   P K + F+W    N L T+    ++ I     CP CN+ PE   H+   C     +W +  +   I     +    W+   ++K +     +  L   T+     WQIWKD+ K   E+I  +P+ +   + I
Sbjct:  305 LLEGRDILLRGAHWQVMNGAHIRLWIDRWLPNSLNDCPRLHSTETLDRNLRVEAIINRELDEWNLDPIRHAISDSDARAITRVKFGS-SRLPDRLIWPMERNGSYSVRSGYHWLHNTECRRRNPRPSSSMTIDPRLWKQIWKADVPPKIRNFLWRALRNCLATSANLHKKKIARSPMCPLCNDHPETAEHILLLCPWVEPVWFRCSLNLRINRQAVTSFGQWLGNVIEKGKTPQERSRCL---TVIAYFCWQIWKDKCKAVLEHISPSPARTTHAASI 578          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPL-DSLYPGNHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTD-NTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNK 564
            ++  G+K   GDG  +  W D+W GD  L  S+   +   LS+KV+  + + +W LQ L   +   ++  I+ +   +     D P W ++ NG FS  ++Y    ++ ++ +  W +IW LK   K K F+WL+  ++L +N  R R+ +    +C  C    E+++ + R CL +  +W +
Sbjct:   18 ILKNGVKIRGGDGLHILFWTDYWFGDDLLIQSVEEMDEDKLSLKVTDYLTHRTWDLQKLKEDLPLEMVAYIICVPA-ELCCKPDSPIWKHTSNGSFSVKSSYRANYQDFSNMDLSWAFIWTLKASPKIKYFLWLLHQDRLLSNEQRVRQRMTLHANCDICGAHVENMDRIIRNCLMASLVWRQ 199          

Query:  262 VADHPTWVNSDNGMFSSSAAYDLI-NRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLW 705
            + D   W  S NG+FS  +AY+++   +   +  WK++WKLK P K   F WLIF  K+ +N  RARR +    SC  C+   E + H+   C+K+ ++WN L         F    Q W+ + L    +       + WN +F+ T W
Sbjct:   15 IQDAQIWKFSPNGIFSVKSAYNMLFEGSACSDVDWKFLWKLKIPPKLHIFFWLIFQGKILSNEQRARRQMSLDASCGSCHWPVESILHILHDCVKARKVWNALLNSSQSAGFFTMDFQPWLKVNL---MSKIVWADGIPWNLVFVFTCW 160          

Query:   49 IGDGNSVDLWKDWWVGDSPLDS-LYPGNHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDL-INRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWN 561
            + +G     W D WVGD PL S L       L +KV   + +G+W L+ L   +   ++  I  ++     + A  P W  + NG FS+ +AY      + + +  W +IW +K P K K F+WL+  +KL TN+ R +R +    +   C    E+  H+ R C  +I +W+
Sbjct:   27 VREGLHTSFWTDNWVGDGPLISRLRRVPQDKLQLKVYDYLSHGTWDLEKLKEALPLEMVGHITCVHAGLSCKPAI-PIWKRTTNGSFSAKSAYMANCQESSSMDVSWAFIWNIKAPPKIKYFLWLLQQDKLLTNYQRVKRKMTMTANFDICGVPMENATHIIRNCPVTISVWH 198          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVG--------DSPLDSLYPGNHTNLSIKVSYLIVN-GS--WYLQNLNH---PIDE-NIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINR----------NPTDNTG--WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWN-KLDVRHLIRNGFESP 606
            I  A  V+  G ++ IGDG SV +W D WV          SPLD +        + KVS LI N GS  W LQ LN+   P+D  +I+ + L I  P      D   W    +G+F+  +AY +  R          +   +TG  W+ IW    PTK K F W + H+ LPT     ++G+   D C  C +  E   H+   C  ++  WN  L  RH  +    SP
Sbjct:  849 IWTARKVLEMGSRFQIGDGKSVRIWGDKWVPRPATFAVITSPLDGME-------NTKVSELICNEGSPQWDLQKLNNLFLPVDVVDIVRIPLSIRAPP-----DRIVWNYDKHGLFTVKSAYRVALRVTSGDEDESSSSNSDTGMLWRHIWNATVPTKLKIFAWRVAHDILPTKANLIKKGVDMQDMCMFCGDITESALHVLAMCPFAVATWNISLLTRHAHQGVQRSP 1065          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVG--------DSPLDSLYPGNHTNLSIKVSYLIVN-GS--WYLQNLNH---PIDE-NIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINR----------NPTDNTG--WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWN-KLDVRHLIRNGFESP 606
            I  A  V+  G ++ IGDG SV +W D WV          SPLD +        + KVS LI N GS  W LQ LN+   P+D  +I+ + L I  P      D   W    +G+F+  +AY +  R          +   +TG  W+ IW    PTK K F W + H+ LPT     ++G+   D C  C +  E   H+   C  ++  WN  L  RH  +    SP
Sbjct: 1329 IWTARKVLEMGSRFQIGDGKSVRIWGDKWVPRPATFAVITSPLDGME-------NTKVSELICNEGSPQWDLQKLNNLFLPVDVVDIVRIPLSIRAPP-----DRIVWNYDKHGLFTVKSAYRVALRVTSGDEDESSSSNSDTGMLWRHIWNATVPTKLKIFAWRVAHDILPTKANLIKKGVDMQDMCMFCGDITESALHVLAMCPFAVATWNISLLTRHAHQGVQRSP 1545          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWV---GDSPLDSLYPGNH-TNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFS-SSAAYDLINRNPTD------------NTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWN-TLFLTTLWQIWKDRNKKSFENIDANP 759
            +L    +I +G  W IG+G SV +WKD W+   G   +  L   N  T L +     + N SW + ++   I  +   LI    I   A   D   W    NG ++  S  Y  IN +P D            +  WK IW+     K + F+W    N +PT      R +    +C  C   PE + HL   C  +  +W      +       + +  W++     +R++ A   Q  W  +LF+   W+IWK R K  F +I  +P
Sbjct:  782 LLVGRDIIEKGAYWQIGNGRSVSVWKDRWLMGYGSGKISPLPSSNRFTPLLVADLIDVGNRSWNISHIEPFIPPSEAMLIRSTPIGSLA-TRDPLVWPAVKNGDYTVKSGYYHAINVSPPDPCDRASSSHAVNSDVWKVIWRAHITPKIRNFMWRALTNSIPTCANLFGRKLARSPTCRLCGLFPETVEHLLLLCSWTRAVWFGCPFGYAPNLASITTLDSWLS---SFLRSSFADGDQRDWGISLFMFCSWEIWKARCKAIFNDIRPSP 1047          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVG--------DSPLDSLYPGNHTNLSIKVSYLIVN-GS--WYLQNLNHPIDENIMNLILDINIPQFAQVA-------DHPTWVNSDNGMFSSSAAYDLINR------------NPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWN-KLDVRHLIRNGFESP 606
            I  A  V+  G ++ IGDG SV +W D WV          SPLD +        + KVS LI N GS  W LQ LN        NL L +++  F ++        D   W    +G+F+  +AY +  R            N   +  W+ IW    PTK K F W + H+ LPT     ++G+   D C  C +  E   H+   C  ++  WN  L  RH  +    SP
Sbjct:  480 IWTARKVLEMGSRFQIGDGKSVRIWGDKWVPRPAAFVVITSPLDGME-------NTKVSELICNEGSPQWDLQKLN--------NLFLPVDVVDFVRIPLSIRAPPDRIVWNYDKHGLFTVKSAYRVALRVTSGDEDESSSSNSDTSMLWRHIWNATVPTKLKIFAWRVAHDILPTKANLIKKGVDMQDMCMFCGDITESALHVLAMCPFAVATWNISLLTRHAHQGVQRSP 696          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPL----DSLYPGNHTNLSIKVSYLIVNGS-WYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSN 765
            I+K   V+   +KW +G+G  ++ W DWWVGD PL    D +   + T+  IKV  LI +   W    L++ +  N+++++    I   ++  D  +W +S  GM + S+AY LI  +  D+    WIW+     K K F+W I  N L  N  R RRG+    SCP C    E L+HLFR CL +   W+        +      +  W+       + +       +W+ +F   LW +WK RN+  F+N    PS+
Sbjct:  915 IMKGKDVLAGAIKWNVGNGRKINFWNDWWVGDGPLASNTDCINQPHMTD--IKVEDLITSQRRWDTGALHNILPTNMIDMVRATPIAINSEQEDFLSWPHSTTGMVTVSSAYSLIAGHDGDDRSHDWIWRATCTEKIKLFMWKIVKNGLMVNVERKRRGLADAASCPVCGEEDETLDHLFRRCLLAEACWDSAVPPLTFQTSNHLHMHSWMKAACSSQQKD---GYSTNWSLIFPYILWNLWKARNRLVFDNNITAPSD 1168          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPL----DSLYPGNHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSN 765
            I+K   V+   +KW +G+G  ++ W DWWVGD PL    D +   + T++ ++         W    L++ +  N+++++    I   ++  D P+W +S  GM + S+AY LI  +  D     WIW+     K K F+W I  N L  N  R RRG+    SCP C    E L+HLFR CL +   W+        +      +  W+       + +       +W+ +F   LW +WK RN+  F+N    PS+
Sbjct: 1447 IMKGKDVLAGAIKWNVGNGRKINFWNDWWVGDGPLASNTDCINQPHMTDIKVE-DLTTSQRRWDTGALHNILPINMIDMVRATPIAINSEQEDFPSWPHSTTGMVTVSSAYSLIAGHDGDGRSHDWIWRATCTEKIKLFMWKIVKNGLMVNVERKRRGLADAASCPVCGEEDETLDHLFRRCLLAEACWDSAVPPLTFQTSNHLHMHSWMKAACSSQQKD---GYGTNWSLIFPYILWNLWKARNRLVFDNNITAPSD 1700          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPL----DSLYPGNHTNLSIKVSYLIVNGS-WYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSN 765
            I+K   V+   +KW +G+G  ++ W DWWVGD PL    D +   + T+  IKV  LI +   W    L++ +  N+++++    I   ++  D  +W +S  GM + S+AY LI  +  D+    WIW+     K K F+W I  N L  N  R RRG+    SCP C    E L+HLFR CL +   W+        +      +  W+       + +       +W+ +F   LW +WK RN+  F+N    PS+
Sbjct:  915 IMKGKDVLAGAIKWNVGNGRKINFWNDWWVGDGPLASNTDCINQPHMTD--IKVEDLITSQRRWDTGALHNILPTNMIDMVRATPIAINSEQEDFLSWPHSTTGMVTVSSAYSLIAGHDGDDRSHDWIWRATCTEKIKLFMWKIVKNGLMVNVERKRRGLADAASCPVCGEEDETLDHLFRRCLLAEACWDSAVPPLTFQTSNHLHMHSWMKAACSSQQKD---GYGTNWSLIFPYILWNLWKARNRLVFDNNITAPSD 1168          

Query:   31 RGMKWVIGDGNSVDLWKDWWVGDSP-LDSLYPGNHTNLSIKVSYLI-VNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTG-WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKK--IRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSN 765
            R + W IGDG S + W D W+ ++  L S    ++ + +I V   I  +G W L  L   +  +I+N IL +  P      D   W  ++   F+  +AY+L   NP    G WK +W  K P + +TFIWL  H ++ TN+ R++ G+    +CP C    E + H+ R C+ S ++W +L   + I N F    ++WV   L K  I +N A      W T F+TT W +W  RNK  FE     PSN
Sbjct:  351 RHVIWQIGDGRSTNFWLDKWISNNTSLFSSSTQSYVDTTISVRDAINTSGVWDLNFLMDNLHVDIVNQILALPTPSDFDGPDTIGWGGTNTLKFTVQSAYNLQQENPFAVGGDWKTLWNWKGPHRIQTFIWLAAHGRILTNYRRSKWGVGISPTCPCCAREDETVIHVLRDCVHSTQVWLRLIPHNYITNFFSFDCREWVFNNLNKKGIGDNPAT-----WQTTFMTTCWYLWNWRNKSIFEIGFQRPSN 595          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSP-------LDSLYPGNHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRN--------PTDN-----TGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVR-----HLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAKLSII--MQWK 798
            IL    +I+RG+K++ G+GN++ LWKD W+  +P        DS+Y        +KVS L++ G W    L   I +N +  I  I  P      D  TW+ + +G +S  + Y L+ +         P+ N     T +  IWK   P K K F W   HN LPT     RR ++T D+C RC  + ED+NHL   C  S E+W +  ++      L+ N F   ++      ++K+ N SA        +LF    W+IWK RN   F N   +  +S + ++I   QWK
Sbjct:  366 ILHGTKLISRGLKYIAGNGNNIQLWKDNWLPLNPPRPPVGTCDSIYS------QLKVSDLLIEGRWNEDLLCKLIHQNDIPHIRAIR-PSITGANDAITWIYTHDGNYSVKSGYHLLRKLSQQQHASLPSPNEVSAQTVFTNIWKQNAPPKIKHFWWRSAHNALPTAGNLKRRRLITDDTCQRCGEASEDVNHLLFQCRVSKEIWEQAHIKLCPGDSLMSNSFNQNLE-----SIQKL-NQSARKDV----SLFPFIGWRIWKMRNDLIFNNKRWSIPDSIQKALIDQQQWK 640          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPL-----DSLYPGNHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAY-----DLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDR 723
            V+ RG+ WV+GDG  +  W+D W+  +PL     D L P       +   Y I    W ++ +   + E +   +L + I     V D  +WV ++NG F+ S+AY     D I++       +  +W++  P + + F+WL+ +  + TN  R RR +   D CP C  + E L H+ R C   + +W ++      R  FE+ + +W+   LK+ R++S   S   W TLF  T+W  WK R
Sbjct:  224 VVNRGIGWVLGDGKIIRFWQDRWLLSTPLLEWVSDQL-PVEERGQRV-ADYWIEGVGWDMERIAVFLPEFMRQRLLAVVIGGCYGVEDKMSWVGTENGRFTVSSAYLIQSVDEISKQCMSRF-FDRVWRVMVPERARIFLWLVGNQVVLTNAERVRRHMADSDVCPLCKGASESLIHVLRDCPAMMGIWMRVVPVMEQRRFFETSLLEWMYGNLKE-RSDSERRS---WPTLFALTVWWGWKWR 460          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSPL-----DSLYPGNHTNLSIKVSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTD--NTG--WKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDR 723
            V+ +G+ WV GDG ++  W D W+   PL     D +  G    + +   Y +    W L+ L   + E +   +L + +  F    D  +W  + +G F+  +AY L+  +  D  N G  +  IWKL TP + + FIWL+  N + TN  R RR +     C  CN + E + H+ R C     +W +L         F   + +W+   +  ++          W TLF   +W  WK R
Sbjct:  783 VVVKGVGWVPGDGCTIRFWLDRWLLQEPLVELGTDMIPEGER--IKVAADYWLPGSGWNLEILGLYLPETVKRRLLSVVVQVFLGNGDEISWKGTQDGAFTVRSAYSLLQGDVGDRPNMGSFFNRIWKLITPERVRVFIWLVSQNVIMTNVERVRRHLSENAICSVCNGAEETILHVLRDCPAMEPIWRRLLPLRRHHEFFSQSLLEWLFTNMDPVKG--------IWPTLFGMGIWWAWKWR 1015          

Query:   49 IGDGNSVDLWKDWWVGDSPLDSLYPG-----NHTNLSIKVSYLIVNGSWYLQNLNHPIDENIM-------NLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELW----NKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSA 771
            +G+G S   WKD W+    +  L P           ++ V+  + N  W +++L  P+   ++       + ++DIN+   +   D   W  + +G +S+++AY  +    +   G K +WK + P + + F+WLI H +  T   R R G+   D C  C+ S E ++HL  GC+ S E+W     +L + HL+    E P+ DW  +Q +K  +      +  +++ F    W +WK+RN ++F+ +    S  A
Sbjct:  940 LGNGRSTLFWKDRWLDGQCIKDLAPAVFQAVKPRKRNVTVAEALQNDVW-VRHLRGPVTAQLLLEISRLFDRLVDINL---SSEPDTFRWGLTADGEYSAASAYGAMFLGSSATVGAKQLWKTRAPPRVRFFVWLILHGRCWTAERRFRHGLQNSDVCIICDQSSETMDHLVLGCVFSREVWGILLRRLHLGHLVIG--EQPVIDW-WLQARKTMDKP---FRAGFDSFFFLMAWNLWKERNARTFQRVQRTASRLA 1186          

Query:   49 IGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIV----NGSWYLQNLNHPIDENIMNLILDIN-----IPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNK-LDVRHLIRN--GFESPIQDWVTIQLKKIRNNSAINSQLH--WNTLFLTTLWQIWKDRNKKSFE 741
            +GDG     W D W+ D PL  L P     +S++     V    +G  ++++++    + IM  I+ ++     +     VAD  TW  + +G +SSS+AY       T   G + +W+ K P K K F WL  H +L T   RAR G+     C  C    E  +HL   C+ S E+W + L + +L ++  G +  + DW       ++  S I++ +   ++++ L   W+IWK+RN+++F+
Sbjct:  664 VGDGERALFWTDSWLPDGPLARLAPRLFHRVSVRNRRRTVRAAMDGERWVRDISGARTQQIMLEIVQVDDRLHAVTLTPGVADKFTWKWTSDGQYSSSSAYRAFFVGSTSLLGARELWQTKAPPKVKFFFWLALHGRLWTAARRARHGLQQSAVCSLCGQQDETSDHLLLACVYSREVWFRLLSIANLQQHAPGTDDILVDW------WLQTRSIIHTDVRKLFDSIVLLVTWEIWKERNRRTFD 902          

Query:   49 IGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVN----GSWYLQNLNHPIDENIMNLILDIN----IPQFAQVADHPT---WVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELW----NKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLH--WNTLFLTTLWQIWKDRNKKSFENIDANP 759
            +GDG +   W D W+    + S  P   + +  +    +V     G  ++++++ PI    M L+++ N    + +  Q++D P    W    NG +S+++AY  +    +   G K IWK   P + + F WL+ H +  T   R R G+ +  +C  C+  PE ++H+  GC  S E+W    NKL ++ L+    E  +  WV       +N   +   L   +++LF    W +WK+RN ++F+ + ++P
Sbjct:  110 LGDGKATYFWTDRWIQGDSIKSFAPNVFSAVRARKRRCLVADALPGDAWVRHISGPIT---MQLLIEFNKICDLLRHIQLSDTPDTFCWRLPGNGTYSAASAYGAMFFGSSLPIGAKEIWKTAAPPRVRFFFWLVLHRRCWTAERRFRHGLQSSATCVMCDQLPETIDHILLGCCFSKEVWHMCLNKLCLQDLVMVNEEHVMSWWV-------KNRKGVPKVLRRGFDSLFFLVGWTLWKERNARTFDAVASSP 353          

Query:   40 KWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHT---NLSIKVSYLIVNG---SW---YLQNLNHPIDENIMNLILDIN-IPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGW--KWIWKLKTPTKFKTFIWLIFHNKLPTNHM---RARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKL 567
            ++V+G+G  + LW+D W GD  L S YP       + +I +S ++ +    SW   + +NL+    E++  L+  ++ + Q   V++   W  S +G+FS  + +  +++       +  K++W  + P K K+F+WL+ H K+ TN M   R      + D C  C    E  +HLF  C  ++ LW++L
Sbjct: 1004 RFVVGNGERILLWEDLWWGDQSLGSQYPRLFRVVMDKNIPISLILGSTHPFSWNFNFHRNLSDSEIEDLEGLMRSLDGLHQSPSVSNARFWPLSYSGLFSIKSFFRALSQFSGSLPVFPSKFVWNSQVPFKVKSFVWLVAHKKVNTNDMLQLRRPYKAPSPDICILCMKHGESADHLFLYCFLTMGLWHRL 1194          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYP-----GNHTNLSIKVSY--LIVNGSWYLQ---NLNH-PIDE--NIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELW 558
            ILK +      +++ +G G  V  W D W G+  L   +P         N S+   +   +  G W ++   N N   +D    +++L+ D+ I   +   D   W     G F    AY L++ +       K IW  K PTK   F W     K+ T     RRG    + C  C    E++NH+   C     LW
Sbjct:  195 ILKDSSWCWDNIEFKVGKGTKVSFWTDHWCGNEVLSQAFPQLFALAVQRNASVNEMWDSSLGQGGWNIRLSRNFNDWELDALGELLHLLRDLRI---SLEEDAVIWKEEGRGRFRIRDAYKLLSGSNVITFPKKSIWVDKVPTKVAFFAWEASWEKVLTLDKLQRRGWQLPNRCFLCGCEEENVNHILLHCTVVRALW 389          

Query:  268 DHPTWVNSDNGMFSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKL----DVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAKLSIIMQWKLTR 807
            D   W  + N  FS  + Y+ ++           IW    P+K   F W     K+ T     +RG    + C  C    E ++H+   C K+  LW+ L     V  ++       + +W    L K         +  W    L   W +W +RN+ +F+N D +        +   W  T+
Sbjct: 4093 DRMMWKVTSNESFSVKSLYNDLSSRRAGLFPHGLIWNPSVPSKVSFFAWEAAWGKVLTMDQLKKRGWAVANRCFMCCEEEESIDHILIHCSKARALWDLLFALFGVCWVLPYSARETLIEWRGFMLGK-------KHRKVWKAAPLCLFWAVWMERNRIAFDNEDFSVHRLKNSFVCNLWVWTK 4269          

Query:   22 VITRGMKWVIGDGNSVDLWKDWWVGDSP------LDSLYPGNHTNLS--IKVSYLIVNGS--WYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAY----DLINRN--------PTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHW---NTLFLTTLWQIWKDRNKKSFENIDAN 756
            ++ +G + V+G+G  + +W+  W+   P      +  + P  + ++S  +KVS LI      W    +     E    LI ++  P   ++ D  TW  + +G ++  + Y     +IN+         P+ N  ++ IWK +T  K + F+W    N LP     A R +    +C RC +  E +NHL   C  +   W    +   I  G E    D + + L  + N    N Q  W   + L    LW++WK+RN+  F   + N
Sbjct:  120 ILRQGARAVVGNGEDIIIWRHKWLDSKPASAALRMQRVPPQEYASVSSILKVSDLIDESGREWRKDVIEMLFPEVERKLIGELR-PGGRRILDSYTWDYTSSGDYTVKSGYWVLTQIINKRSSPQEVSEPSLNPIYQKIWKSQTSPKIQHFLWKCLSNSLPVAGALAYRHLSKESACIRCPSCKETVNHLLFKCTFARLTWAISSIP--IPLGGE--WADSIYVNLYWVFNLGNGNPQ--WEKASQLVPWLLWRLWKNRNELVFRGREFN 382          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDS-LYPGNHTNLSIKVSYLIV----NGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGM---FSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAKLSI 783
            +++  P I   M+  +G+G S   W D W     L + L       L I+    +V    NG W+L        +  +  +    +P  ++  D   W N+       FSS   ++ I  +       K +W  +   +F    W+ F  +LPT       G+    S   C+N  E   HLF  C  S+ +W     +      F  P      +QL  +R++S    +L    L  + ++ +WK+RN + F +I ++ S S +L+I
Sbjct:    1 MIQLKPSIVEFMRCDMGNGESASFWYDAWTDFGQLLTFLGAAGPRQLRIRQDARVVEASRNGDWFLPAARSDNSQLFLAALTMAPVPHESRGQDSFLWRNAAGSYLPSFSSRDTWEQIRVHSPTVPWAKVVWFKEYIPRFSLITWMSFLERLPTRDRLRGWGMNIPSSWVLCSNGDETHAHLFFECSFSLAIWEFFASKFRPSPPFGLPAASSWILQL-PLRSHSTTILKL----LLQSAVYHVWKERNARIFTSISSSAS-SLRLAI 262          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIKVSYLIVN-GSWYL---QNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGMFSSSAAYDLINRNPTDNTGW-----------KWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFES-PIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNS 768
            +L    ++ +G + +IGDG ++ +  D  V   P   L     T   + ++ L    GS+Y      ++  +D++    I  I + + ++  D   W  +  G ++  + Y L+  +P+ N                IW L    K K F+W      L T      RG+    SCPRC+   E +NH    C  +   W +L    LIRN   S   ++ ++  L  +++ +   S  H   L +  +W+IWK RN   F     +PS +
Sbjct:   27 LLDGIALLKKGTRHLIGDGQNIRIGLDNIVDSHPPRPLNT-EETYKEMTINNLFERKGSYYFWDDSKISQFVDQSDHGFIHRIYLAK-SKKPDKIIWNYNTTGEYTVRSGYWLLTHDPSTNIPAINPPHGSIDLKTRIWNLPIMPKLKHFLWRALSQALATTERLTTRGMRIDPSCPRCHRENESINHALFTCPFATMAW-RLSDSSLIRNQLMSNDFEENISNILNFVQDTTM--SDFH-KLLPVWLIWRIWKARNNVVFNKFRESPSKT 291          

Query:  370 IWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRH--LIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAK--LSIIMQWKLT 804
            IWKLKT  K K F+W +    L T     RR I     C RC    E   HLF  C  + ++W    + H  L   G        +  +++ + ++   N Q     L +  LW++WK RN+  F+    +  N+ +   + + +W+ T
Sbjct:   18 IWKLKTAPKIKHFLWKLLSGALATGDNLKRRHIRNHPQCHRCCQEDETSQHLFFDCFYAQQVWRASGIPHQELRTTGIT------METKMELLLSSCLANRQPQLFNLAIWILWRLWKSRNQLVFQQKSISWQNTLQRARNDVQEWEDT 160          

Query:    4 ILKANPVITRGMKWVIGDGNSVDLWKDWWVGDSPLDSLYPGNHTNLSIK-------VSYLIVNGSWYLQNLNHPIDENIMNLILDINIPQFAQVADHPTWVNSDNGM--FSSSAAYDLINRNPTDNTGWKWIWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVTIQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANP 759
            +L   P+  + +K  +G+G     W D W    PL  +  G++ + S++       V  L VNG W L        + I + I  I  P  A + D   WV        FSS+  +D I     +    K +W      K    +W+   ++LPT    A  G +    C  C    E  +HL   C  + ++W     R   R   +     W  + L  +R++S+    L         ++ IW+ RN     N+   P
Sbjct:    2 LLFLRPLAEQFVKCNLGNGRIAHFWHDSWTSLGPLIKVM-GDYGSRSLRIPLNARVVEALGVNG-WKLPLSRSAPAQAIHDHISTITTPSPATIEDSFDWVVGGVVCQGFSSARTWDAIRPRAPELDWAKAVWFKGAVPKHAFNMWISQLDRLPTRQRLASWGHIQSFDCCLCTIETESRDHLLFSCEFAAQVWRLAFSRLCPR---QRLFCSWAEL-LSWMRSSSSSAPSLLRKVSAHAIIYNIWRQRNNVLHNNLRIAP 256          

Query:  370 IWKLKTPTKFKTFIWLIFHNKLPTNHMRARRGIVTLDSCPRCNNSPEDLNHLFRGCLKSIELWNKLDVRHLIRNGFESPIQDWVT--IQLKKIRNNSAINSQLHWNTLFLTTLWQIWKDRNKKSFENIDANPSNSAKLSI 783
            IWKL    K K F+W      L TN     R I     C RC    E ++H+   C  +  +W   ++    + G  S  +D +   IQL K +  ++++  L +       +W++WK RN   F+    +P   A+  I
Sbjct:   37 IWKLHVAPKIKHFLWRCVTGALATNTRLRSRNIDADPICQRCCIEEETIHHIMFNCPYTQSVWRSANIIIGNQWGPPSSFEDNLNRLIQLSKTQTTNSLDRFLPF-----WIMWRLWKSRNVFLFQQKCQSPDYEARKGI 171